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Current advances in the elimination of hepatitis B in China by 2030

Shuye Zhang, Fusheng Wang, Zheng Zhang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 490-501 doi: 10.1007/s11684-017-0598-4

Abstract: Available anti-HBV therapy is efficacious in suppressing HBV replication; however, it fails to completely cure

Keywords： HBV     CHB     biomarker     functional cure     coinfection    

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Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 502-508 doi: 10.1007/s11684-017-0590-z

Abstract: loss of serum HBV RNA accompanied with low serum HBsAg levels might be implicated as a “para-functionalcure,” a status nearly close to the functional cure of chronic hepatitis B, to distinguish the“functional cure” characterized as serum HBsAg loss with or without anti-HBs seroconversion

Keywords： chronic hepatitis B     serum HBV RNA     nucleos(t)ide analogs     virological response     para-functional cure    

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Improved “cure on demand” of aromatic bismaleimide with thiol triggered by retro-Diels-Alder reaction

Vincent Froidevaux, Mélanie Decostanzi, Abdelatif Manseri, Sylvain Caillol, Bernard Boutevin, Rémi Auvergne

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 330-339 doi: 10.1007/s11705-020-1929-6

Abstract: This study focuses on the synthesis of new liquid aromatic bismaleimide monomers in order to improve self-curing on demand (SCOD) systems previously based on aliphatic bismaleimides. These SCOD systems are based on Diels-Alder (DA)/retro-DA reactions. The syntheses of new different aromatic bismaleimides with ester and amide bonds are presented. These maleimides have been protected using DA reaction and characterized by H NMR analysis to determine protection rate and diastereomer ratios. The retro-DA reactions of both aromatic and aliphatic DA adducts in presence of thiol molecules were studied. Kinetic analysis was monitored by H NMR and compared to model study. Finally, both aromatic and aliphatic bismaleimides-based polymers were synthesized with 2-mercaptoethyl ether and thermal properties of polymers were compared. The glass transition temperature values ranged from –20 °C to 14 °C and very good thermal stabilities were observed (up to 300 °C).

Keywords： thiol-ene polymerization     self-curing on demand     thia-michael addition     Diels-Alder     maleimide    

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Thinking about Future Plant Medicine Engineering

Gao Jinji

Strategic Study of CAE 2003, Volume 5, Issue 12,   Pages 30-35

Abstract:

According to the dissipative structure theory, human has much in common with man-made machine, and there is much in resemblance between disease healing of human and fault overcoming of machine. Under the light of the systemics, by introducing the methodology of medical science into the field of machine fault diagnosis, prediction and prevention, it is possible to build a new theory of PME (Plant Medicine Engineering) to prevent and eliminate faults of machine by engineering means. Some common issues, such as the forming of diseases and faults, how to diagnose those diseases and faults, the deep rule concerning the causes and mechanisms of faults and diseases, comparison between curing and self-healing, and between the dealing of symptoms and that of initial causes, etc. , were discussed in this paper. A novel “crystal box approach” of PME, which is based on the piths of both “black-box approach” of traditional Chinese medical theory and uwhite-box approach^ of modern west medical science, was put forth. Lastly, from the view point df PME, some pitfalls in current studies about fault diagnosis are discussed.

Keywords： plant medicine engineering     diseases     faults     prevention and cure    

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Development and applications of functional gene microarrays in the analysis of the functional diversity

Zhili HE, Joy D. VAN NOSTRAND, Ye DENG, Jizhong ZHOU

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 1,   Pages 1-20 doi: 10.1007/s11783-011-0301-y

Abstract: Functional gene arrays (FGAs) are a special type of microarrays containing probes for key genes involvedin microbial functional processes, such as biogeochemical cycling of carbon, nitrogen, sulfur, phosphorusSeveral generations of GeoChip have been developed and applied to investigate the functional diversity

Keywords： functional gene arrays (FGAs)     GeoChip     microbial communities     functional diversity/composition/structure    

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Fluorescent probes and functional materials for biomedical applications

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1425-1437 doi: 10.1007/s11705-022-2163-1

Abstract: Here, we highlight examples of fluorescent probes and functional materials for biological applications

Keywords： fluorescent probes     imaging     cell     biomedicine     biomolecules    

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Phase separation time/temperature dependence of thermoplastics-modified thermosetting systems

ZHANG Xiujuan, XU Yuanze, YI Xiaosu

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 3,   Pages 276-285 doi: 10.1007/s11705-008-0057-5

Abstract: The cure-induced phase separation processes of various thermoplastics(TP)-modified thermosetting systemsemphasis on the temperature dependency of the phase separation time and its potential application in the cureThe cure-induced phase separation activation energy (ps) generated from the linear fitting of the Arrheniusthat (ps) is insensitive to TP content, TP molecular weight and curing rate, but it changes with the cureestablished phase separation time-temperature dependence relation, we can easily establish the whole cure

Keywords： separation time-temperature     temperature dependency     cure-induced     separation activation     temperature    

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Temporal dimension and water quality control in an emission trading scheme based on water environmental functional

Zhaoxing HAN, Zhenyao SHEN, Yongwei GONG, Qian HONG

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 1,   Pages 119-129 doi: 10.1007/s11783-011-0272-z

Abstract: Water environmental functional zone (WEFZ) is used to determine the water quality standard and identifyA water quality-control scheme was suggested based on the water quality requirement in the water functional

Keywords： emission trading     water functional zone     water quality control    

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A Study of the Functional Mechanism of Petrochemical Engineering Construction Project Management

Ji-ming Wang

Frontiers of Engineering Management 2014, Volume 1, Issue 2,   Pages 129-139 doi: 10.15302/J-FEM-2014020

Abstract: This paper, proceeding from the project construction process, the management mode and the implementation way, makes an in-depth study of the environmental characteristics and the managerial elements of petrochemical engineering construction project, revealing the inherent laws, establishing a theoretical model, and proposing a theory of the mechanisms of construction project management; and presents profound revelations found for construction project management in petrochemical engineering in seven aspects, which can play a guiding role in improving the managerial performance of petrochemical construction project. The theory established proposes that: The construction project management in petrochemical engineering is a complex systematic process, formed of 5 phases and 55 sub-processes of management, and exposed to many factors of influence; the environmental characteristics and managerial elements exercise positive impacts on managerial performance, but different factors have different impacts and act in different ways on managerial performance; the managerial elements of petrochemical engineering construction project are tiered, transferable, systematic and quantifiable, and the role of managerial elements in the managerial performance can be systematically integrated, quantitatively explained and transferred in a multi-level way.

Keywords： petrochemical engineering     construction project     project management     functional mechanism    

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Effects of functional groups for CO

Chenkai Gu, Yang Liu, Weizhou Wang, Jing Liu, Jianbo Hu

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 437-449 doi: 10.1007/s11705-020-1961-6

Abstract: Functional groups on organic linkers of MOFs play important roles in improving the CO capture abilityfunctionalization effects on CO adsorption were systematically investigated by rationally incorporating various functionalIn addition, three kinds of molecular interactions between CO and functional groups were analyzed andEspecially, our results reveal that –SO H is the best-performing functional group for CO capture in

Keywords： metal-organic frameworks     functional groups     CO2 capture     GCMC     DFT    

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Microbial community and functional genes in the rhizosphere of alfalfa in crude oil-contaminated soil

Yi ZHONG, Jian WANG, Yizhi SONG, Yuting LIANG, Guanghe LI

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 6,   Pages 797-805 doi: 10.1007/s11783-012-0405-z

Abstract: vegetated with alfalfa ( L.) to evaluate the rhizosphere effects on the soil microbial population and functionalIn total, 796, 731, and 379 functional genes were detected by microarray in the AR, FR, and NR, respectivelyHigher proportions of functional genes related to carbon degradation and organic remediation, were foundwith NR soil, suggesting that the rhizosphere selectively increased the abundance of these specific functionalanalysis showed that salinity was the most important environmental factor influencing the microbial functional

Keywords： crude oil-contaminated soil     phytoremediation     rhizosphere effects     rhizobox     functional genes    

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Behavioral methods for the functional assessment of hair cells in zebrafish

Qin Yang, Peng Sun, Shi Chen, Hongzhe Li, Fangyi Chen

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 178-190 doi: 10.1007/s11684-017-0507-x

Abstract:

Zebrafish is an emerging animal model for studies on auditory system. This model presents high comparability with humans, good accessibility to the hearing organ, and high throughput capacity. To better utilize this animal model, methodologies need to be used to quantify the hearing function of the zebrafish. Zebrafish displays a series of innate and robust behavior related to its auditory function. Here, we reviewed the advantage of using zebrafish in auditory research and then introduced three behavioral tests, as follows: the startle response, the vestibular-ocular reflex, and rheotaxis. These tests are discussed in terms of their physiological characteristics, up-to-date technical development, and apparatus description. Test limitation and areas to improve are also introduced. Finally, we revealed the feasibility of these applications in zebrafish behavioral assessment and their potential in the high-throughput screening on hearing-related genes and drugs.

Keywords： zebrafish (Danio rerio)     behavior     auditory     startle response     vestibular-ocular reflex     rheotaxis    

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Characterization and comparison of organic functional groups effects on electrolyte performance for vanadium

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 9,   Pages 1221-1230 doi: 10.1007/s11705-023-2298-8

Abstract: energy density and stability limitations, as well as to investigate the effects of various organic functional

Keywords： vanadium redox flow battery     functional groups     organic additives     energy density     stability    

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A density functional theory study on the mechanism of Dimethyl ether carbonylation over heteropolyacids

Kai Cai, Ying Li, Hongbao Shen, Zaizhe Cheng, Shouying Huang, Yue Wang, Xinbin Ma

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 2,   Pages 319-329 doi: 10.1007/s11705-020-1957-2

Abstract: In this work, the reaction mechanism of DME carbonylation was studied theoretically by using density functional

Keywords： dimethyl ether     carbonylation     mechanism     heteropolyacids     density functional theory    

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EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 740-749 doi: 10.1007/s11684-020-0794-5

Abstract: novel artificial neural rehabilitation system, which integrates brain--computer interface (BCI) and functional

Keywords： brain–computer interface     functional electrical stimulation     electroencephalogram     laterality coefficient    

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Title Author Date Type Operation

Current advances in the elimination of hepatitis B in China by 2030

Shuye Zhang, Fusheng Wang, Zheng Zhang

Journal Article

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Journal Article

Improved “cure on demand” of aromatic bismaleimide with thiol triggered by retro-Diels-Alder reaction

Vincent Froidevaux, Mélanie Decostanzi, Abdelatif Manseri, Sylvain Caillol, Bernard Boutevin, Rémi Auvergne

Journal Article

Thinking about Future Plant Medicine Engineering

Gao Jinji

Journal Article

Development and applications of functional gene microarrays in the analysis of the functional diversity

Zhili HE, Joy D. VAN NOSTRAND, Ye DENG, Jizhong ZHOU

Journal Article

Fluorescent probes and functional materials for biomedical applications

Journal Article

Phase separation time/temperature dependence of thermoplastics-modified thermosetting systems

ZHANG Xiujuan, XU Yuanze, YI Xiaosu

Journal Article

Temporal dimension and water quality control in an emission trading scheme based on water environmental functional

Zhaoxing HAN, Zhenyao SHEN, Yongwei GONG, Qian HONG

Journal Article

A Study of the Functional Mechanism of Petrochemical Engineering Construction Project Management

Ji-ming Wang

Journal Article

Effects of functional groups for CO

Chenkai Gu, Yang Liu, Weizhou Wang, Jing Liu, Jianbo Hu

Journal Article

Microbial community and functional genes in the rhizosphere of alfalfa in crude oil-contaminated soil

Yi ZHONG, Jian WANG, Yizhi SONG, Yuting LIANG, Guanghe LI

Journal Article

Behavioral methods for the functional assessment of hair cells in zebrafish

Qin Yang, Peng Sun, Shi Chen, Hongzhe Li, Fangyi Chen

Journal Article

Characterization and comparison of organic functional groups effects on electrolyte performance for vanadium

Journal Article

A density functional theory study on the mechanism of Dimethyl ether carbonylation over heteropolyacids

Kai Cai, Ying Li, Hongbao Shen, Zaizhe Cheng, Shouying Huang, Yue Wang, Xinbin Ma

Journal Article

EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and

Journal Article